| Item Type | Name |
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Concept
|
Actins
|
|
Concept
|
Acetylation
|
|
Concept
|
Acyltransferases
|
|
Concept
|
Cyclic AMP
|
|
Concept
|
Aldehyde-Lyases
|
|
Concept
|
Animals
|
|
Concept
|
Animals, Newborn
|
|
Concept
|
Antioxidants
|
|
Concept
|
Analysis of Variance
|
|
Concept
|
Asthma
|
|
Concept
|
Cell Count
|
|
Concept
|
Cell Movement
|
|
Concept
|
Capillary Permeability
|
|
Concept
|
Bronchoalveolar Lavage Fluid
|
|
Concept
|
Carbon Tetrachloride
|
|
Concept
|
Cartilage, Articular
|
|
Concept
|
Catalase
|
|
Concept
|
Chemotaxis
|
|
Concept
|
Genetic Vectors
|
|
Concept
|
C-Reactive Protein
|
|
Concept
|
Glutathione Peroxidase
|
|
Concept
|
Glutathione Transferase
|
|
Concept
|
Cholesterol
|
|
Concept
|
Collagen
|
|
Concept
|
DNA, Mitochondrial
|
|
Concept
|
Injections, Intraperitoneal
|
|
Concept
|
Endothelium, Vascular
|
|
Concept
|
Enzyme Inhibitors
|
|
Concept
|
Lysophospholipids
|
|
Concept
|
Amifostine
|
|
Concept
|
Fibroblasts
|
|
Concept
|
Enzyme Activation
|
|
Concept
|
Gene Expression Regulation
|
|
Concept
|
Atrial Natriuretic Factor
|
|
Concept
|
Fibronectins
|
|
Concept
|
Obesity
|
|
Concept
|
Hematopoietic Stem Cells
|
|
Concept
|
Dose-Response Relationship, Drug
|
|
Concept
|
Hydrogen Peroxide
|
|
Concept
|
Fluorescent Antibody Technique
|
|
Concept
|
Inflammation
|
|
Concept
|
Lung Diseases
|
|
Concept
|
Membrane Glycoproteins
|
|
Concept
|
Microfilament Proteins
|
|
Concept
|
Phosphatidylcholines
|
|
Concept
|
Phospholipase D
|
|
Concept
|
Phospholipids
|
|
Concept
|
Myocardial Infarction
|
|
Concept
|
Mice, Transgenic
|
|
Concept
|
Immunohistochemistry
|
|
Concept
|
Mice, Inbred C57BL
|
|
Concept
|
Random Allocation
|
|
Concept
|
Lipopolysaccharides
|
|
Concept
|
Microscopy, Electron
|
|
Concept
|
Placental Hormones
|
|
Concept
|
Oxygen
|
|
Concept
|
Epoprostenol
|
|
Concept
|
Pyridines
|
|
Concept
|
Histone Deacetylases
|
|
Concept
|
Receptors, Cell Surface
|
|
Concept
|
Pyrrolidines
|
|
Concept
|
Receptors, LDL
|
|
Concept
|
Cohort Studies
|
|
Concept
|
Cadherins
|
|
Concept
|
Interleukin-6
|
|
Concept
|
Ribonuclease, Pancreatic
|
|
Concept
|
Sensitivity and Specificity
|
|
Concept
|
Thrombin
|
|
Concept
|
Humans
|
|
Concept
|
Hypertension, Pulmonary
|
|
Concept
|
Stress, Mechanical
|
|
Concept
|
Electric Impedance
|
|
Concept
|
Tumor Necrosis Factor-alpha
|
|
Concept
|
Hepatocyte Growth Factor
|
|
Concept
|
Drug Design
|
|
Concept
|
Dinoprostone
|
|
Concept
|
Hematopoietic Stem Cell Transplantation
|
|
Concept
|
Hyperoxia
|
|
Concept
|
Reverse Transcriptase Polymerase Chain Reaction
|
|
Concept
|
Guanine Nucleotide Exchange Factors
|
|
Concept
|
rho GTP-Binding Proteins
|
|
Concept
|
Tyrosine
|
|
Concept
|
rac1 GTP-Binding Protein
|
|
Concept
|
Transforming Growth Factor beta
|
|
Concept
|
Cell Adhesion Molecules
|
|
Concept
|
8-Bromo Cyclic Adenosine Monophosphate
|
|
Concept
|
Lipid Peroxidation
|
|
Concept
|
Antigens, CD
|
|
Concept
|
Mitochondria
|
|
Concept
|
Paclitaxel
|
|
Concept
|
Proto-Oncogene Proteins c-abl
|
|
Concept
|
RNA Interference
|
|
Concept
|
Melanoma
|
|
Concept
|
Gene Transfer Techniques
|
|
Concept
|
Gene Deletion
|
|
Concept
|
Mice, Knockout
|
|
Concept
|
Pneumonia, Bacterial
|
|
Concept
|
DNA, Complementary
|
|
Concept
|
Cell Proliferation
|
|
Concept
|
Immunomagnetic Separation
|
|
Concept
|
beta Catenin
|
|
Concept
|
Proto-Oncogene Proteins c-vav
|
|
Concept
|
Simvastatin
|
|
Concept
|
Tyrphostins
|
|
Concept
|
Transgenes
|
|
Concept
|
Angiogenesis Inhibitors
|
|
Concept
|
Gene Regulatory Networks
|
|
Concept
|
Chondrocytes
|
|
Concept
|
Protein Tyrosine Phosphatases, Non-Receptor
|
|
Concept
|
Reactive Oxygen Species
|
|
Concept
|
Cortactin
|
|
Concept
|
CD146 Antigen
|
|
Concept
|
Interleukin-1beta
|
|
Concept
|
rac GTP-Binding Proteins
|
|
Concept
|
rap1 GTP-Binding Proteins
|
|
Concept
|
Active Transport, Cell Nucleus
|
|
Concept
|
Platelet Endothelial Cell Adhesion Molecule-1
|
|
Concept
|
Gene Expression Profiling
|
|
Concept
|
Phosphatidic Acids
|
|
Concept
|
Phenazines
|
|
Concept
|
Phosphoric Monoester Hydrolases
|
|
Concept
|
Plasmalogens
|
|
Concept
|
Pneumonia
|
|
Concept
|
Pseudomonas aeruginosa
|
|
Concept
|
Mice
|
|
Concept
|
Focal Adhesion Kinase 1
|
|
Concept
|
Pyrazoles
|
|
Concept
|
Rats, Inbred BN
|
|
Concept
|
Transforming Growth Factor beta1
|
|
Concept
|
Radiation-Protective Agents
|
|
Concept
|
Ribonucleases
|
|
Concept
|
Tandem Mass Spectrometry
|
|
Concept
|
Pulmonary Surfactant-Associated Protein C
|
|
Concept
|
Acute Lung Injury
|
|
Concept
|
Histone Deacetylase 2
|
|
Concept
|
Molecular Targeted Therapy
|
|
Concept
|
Rats
|
|
Concept
|
Paxillin
|
|
Concept
|
High-Throughput Nucleotide Sequencing
|
|
Concept
|
Sphingolipids
|
|
Concept
|
Adaptor Proteins, Signal Transducing
|
|
Concept
|
Immunoblotting
|
|
Concept
|
Blotting, Western
|
|
Concept
|
Down-Regulation
|
|
Concept
|
Histone Deacetylase 1
|
|
Concept
|
Mice, 129 Strain
|
|
Concept
|
Transfection
|
|
Concept
|
Genetic Therapy
|
|
Concept
|
Gene Expression Regulation, Enzymologic
|
|
Concept
|
Free Radical Scavengers
|
|
Concept
|
NADPH Oxidases
|
|
Concept
|
Proto-Oncogene Proteins c-met
|
|
Concept
|
Gene Silencing
|
|
Concept
|
Cell-Derived Microparticles
|
|
Concept
|
Gene Knockdown Techniques
|
|
Concept
|
Anion Transport Proteins
|
|
Concept
|
Alveolar Epithelial Cells
|
|
Concept
|
Phosphatidylinositol 3-Kinases
|
|
Concept
|
Monomeric GTP-Binding Proteins
|
|
Concept
|
MAP Kinase Signaling System
|
|
Concept
|
Receptors, Lysophosphatidic Acid
|
|
Concept
|
Caveolin 1
|
|
Concept
|
Pulmonary Disease, Chronic Obstructive
|
|
Concept
|
AMP-Activated Protein Kinases
|
|
Concept
|
Ventilator-Induced Lung Injury
|
|
Concept
|
RNA, Small Interfering
|
|
Concept
|
Amyloid Precursor Protein Secretases
|
|
Concept
|
rho-Associated Kinases
|
|
Concept
|
Idiopathic Pulmonary Fibrosis
|
|
Concept
|
Airway Remodeling
|
|
Concept
|
Methanol
|
|
Concept
|
Allergens
|
|
Concept
|
Benzenesulfonates
|
|
Concept
|
Bronchopulmonary Dysplasia
|
|
Concept
|
Cell Survival
|
|
Concept
|
Cloning, Molecular
|
|
Concept
|
Disease Models, Animal
|
|
Concept
|
Immunoglobulins
|
|
Concept
|
Microscopy, Fluorescence
|
|
Concept
|
Phosphatidylserines
|
|
Concept
|
Phosphoric Diester Hydrolases
|
|
Concept
|
Respiration, Artificial
|
|
Concept
|
Sphingosine
|
|
Concept
|
Staining and Labeling
|
|
Concept
|
Cytokines
|
|
Concept
|
Iloprost
|
|
Concept
|
Cyclic AMP-Dependent Protein Kinases
|
|
Concept
|
DNA Primers
|
|
Concept
|
Hyaluronan Receptors
|
|
Concept
|
Neural Cell Adhesion Molecules
|
|
Concept
|
Membrane Microdomains
|
|
Concept
|
Epigenesis, Genetic
|
|
Concept
|
p38 Mitogen-Activated Protein Kinases
|
|
Concept
|
Receptors, Lysosphingolipid
|
|
Concept
|
Proto-Oncogene Proteins c-akt
|
|
Concept
|
p21-Activated Kinases
|
|
Concept
|
Lung Injury
|
|
Concept
|
Sirtuin 1
|
|
Academic Article
|
Serum C-reactive protein and circulating endothelial cells in patients with acute myocardial infarction.
|
|
Academic Article
|
Amifostine reduces lung vascular permeability via suppression of inflammatory signalling.
|
|
Academic Article
|
Rac GTPase is a hub for protein kinase A and Epac signaling in endothelial barrier protection by cAMP.
|
|
Academic Article
|
Polar head groups are important for barrier-protective effects of oxidized phospholipids on pulmonary endothelium.
|
|
Academic Article
|
p190RhoGAP mediates protective effects of oxidized phospholipids in the models of ventilator-induced lung injury.
|
|
Academic Article
|
Prostaglandins PGE(2) and PGI(2) promote endothelial barrier enhancement via PKA- and Epac1/Rap1-dependent Rac activation.
|
|
Academic Article
|
Lung endothelial barrier protection by iloprost in the 2-hit models of ventilator-induced lung injury (VILI) involves inhibition of Rho signaling.
|
|
Academic Article
|
Protection of LPS-induced murine acute lung injury by sphingosine-1-phosphate lyase suppression.
|
|
Academic Article
|
Induction of cellular antioxidant defense by amifostine improves ventilator-induced lung injury.
|
|
Academic Article
|
The antioxidant effects of ribonuclease inhibitor.
|
|
Academic Article
|
Role of c-Met/phosphatidylinositol 3-kinase (PI3k)/Akt signaling in hepatocyte growth factor (HGF)-mediated lamellipodia formation, reactive oxygen species (ROS) generation, and motility of lung endothelial cells.
|
|
Academic Article
|
Autotaxin production of lysophosphatidic acid mediates allergic asthmatic inflammation.
|
|
Academic Article
|
c-Abl mediated tyrosine phosphorylation of paxillin regulates LPS-induced endothelial dysfunction and lung injury.
|
|
Academic Article
|
Role played by paxillin and paxillin tyrosine phosphorylation in hepatocyte growth factor/sphingosine-1-phosphate-mediated reactive oxygen species generation, lamellipodia formation, and endothelial barrier function.
|
|
Academic Article
|
Hyperoxia-induced p47phox activation and ROS generation is mediated through S1P transporter Spns2, and S1P/S1P1&2 signaling axis in lung endothelium.
|
|
Academic Article
|
Sphingolipids Signaling in Lamellipodia Formation and Enhancement of Endothelial Barrier Function.
|
|
Academic Article
|
Sphingosine-1-phosphate mediates the therapeutic effects of bone marrow mesenchymal stem cell-derived microvesicles on articular cartilage defect.
|
|
Academic Article
|
Role of Sphingosine Kinase 1 and S1P Transporter Spns2 in HGF-mediated Lamellipodia Formation in Lung Endothelium.
|
|
Academic Article
|
Pseudomonas aeruginosa stimulates nuclear sphingosine-1-phosphate generation and epigenetic regulation of lung inflammatory injury.
|
|
Academic Article
|
Role of phospholipase D in bleomycin-induced mitochondrial reactive oxygen species generation, mitochondrial DNA damage, and pulmonary fibrosis.
|
|
Academic Article
|
Genetic deletion of Sphk2 confers protection against Pseudomonas aeruginosa mediated differential expression of genes related to virulent infection and inflammation in mouse lung.
|
|
Academic Article
|
Sphingosine Kinase 1/S1P Signaling Contributes to Pulmonary Fibrosis by Activating Hippo/YAP Pathway and Mitochondrial Reactive Oxygen Species in Lung Fibroblasts.
|
|
Academic Article
|
Advancements in understanding the role of lysophospholipids and their receptors in lung disorders including bronchopulmonary dysplasia.
|
|
Academic Article
|
S1P and plasmalogen derived fatty aldehydes in cellular signaling and functions.
|
|
Academic Article
|
Phospholipase D2 restores endothelial barrier function by promoting PTPN14-mediated VE-cadherin dephosphorylation.
|
|
Academic Article
|
Angiocrine Sphingosine-1-Phosphate Activation of S1PR2-YAP Signaling Axis in Alveolar Type II Cells Is Essential for Lung Repair.
|
|
Academic Article
|
Neonatal therapy with PF543, a sphingosine kinase 1 inhibitor, ameliorates hyperoxia-induced airway remodeling in a murine model of bronchopulmonary dysplasia.
|
|
Academic Article
|
NOX4 Mediates Pseudomonas aeruginosa-Induced Nuclear Reactive Oxygen Species Generation and Chromatin Remodeling in Lung Epithelium.
|
|
Academic Article
|
Nuclear Sphingosine-1-phosphate Lyase Generated ?2-hexadecenal is A Regulator of HDAC Activity and Chromatin Remodeling in Lung Epithelial Cells.
|
|
Academic Article
|
Hyperoxia-induced S1P1 signaling reduced angiogenesis by suppression of TIE-2 leading to experimental bronchopulmonary dysplasia.
|
|
Academic Article
|
Essential role for paxillin tyrosine phosphorylation in LPS-induced mitochondrial fission, ROS generation and lung endothelial barrier loss.
|
|
Academic Article
|
Role of Lysocardiolipin Acyltransferase in Cigarette Smoke-Induced Lung Epithelial Cell Mitochondrial ROS, Mitochondrial Dynamics, and Apoptosis.
|
|
Academic Article
|
Do nicotine dependence influencing and non-influencing behaviors have an association with high nicotine dependence in smokers?
|
|
Academic Article
|
NOX4 Mediates Epithelial Cell Death in Hyperoxic Acute Lung Injury Through Mitochondrial Reactive Oxygen Species.
|
|
Concept
|
ADAM10 Protein
|
|
Concept
|
NADPH Oxidase 2
|
|
Concept
|
NADPH Oxidase 4
|
|
Concept
|
T-Lymphoma Invasion and Metastasis-inducing Protein 1
|
|
Concept
|
Zonula Occludens-1 Protein
|
|
Concept
|
Mitochondrial Dynamics
|
|
Concept
|
Occludin
|
|
Concept
|
Rho Guanine Nucleotide Exchange Factors
|
|
Concept
|
Vascular Remodeling
|
|
Academic Article
|
Metabolic reprogramming, oxidative stress, and pulmonary hypertension.
|
|
Academic Article
|
Sphingosine-1-Phosphate Receptor 3 Induces Endothelial Barrier Loss via ADAM10-Mediated Vascular Endothelial-Cadherin Cleavage.
|
|
Academic Article
|
The value of calcofluor white in the diagnosis of invasive fungal diseases.
|
|
Academic Article
|
Amifostine ameliorates bleomycin-induced murine pulmonary fibrosis via NAD+/SIRT1/AMPK pathway-mediated effects on mitochondrial function and cellular metabolism.
|